Here are 10, but I am sure there are more. What are your suggestions?

From the Visit Grand Junction website, if you are unfamiliar with this area, here is what you need to know.

Colorado National Monument - It's a National treasure right in our own backyard. A 23 mile stretch of breathtaking scenery along Rim Rock Road. Not to mention countless miles of hiking opportunities. Stay for a day or camp out on one of the 80 campsites at Saddle Horn. 

Keyes
Keyes
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Take a Wine Tour - With 22 wineries all in earshot of each other, there are endless opportunities to taste wine, tour a winery or just spend time with friends and family. Special events such as bachelorette parties are welcome too!

Colorado Dog Wine
Thinkstock
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Mountain Biking - From the Lunch Loop to the Kokopelli Trails, you won't run out of trails to hit. Difficulty ranges from beginner to expert. There is a trail for everyone.

2010 24 Hours of Moab
Doug Pensinger
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Hit the Links - There are five world-class golf courses to choose from. The beautiful weather combined with the backdrop of the Grand Valley scenery will make you want to play at least 18 holes every day.

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Otmar Winterleitner
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Lavender Fest - Held in Palisade, actually, but it's so unique you have to check it out. A  celebration of a very interesting plant. Music, food, lavender farm tours and more! Usually held the weekend after July 4th.

Lavender Fields In The Surrey Hills
Getty Images
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Museum of the West - Discover what is what really like back in the wild, wild west. Numerous exhibits and interactive displays. Definitely plan for a long, but education day.

Old West Homestead Portrait
Getty Images
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Colorado Wine Festival - Held every year third week in September. It's the largest in Colorado and has been voted as one of the best fests in the country! With dozens and dozens of vendors, your palette and your thirst will not go quenched.

Colorado Mountain Winefest
Brian Wiley via Youtube
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Tackle the Colorado River - Whether you want to slowly travel down the mighty Colorado or if you want a full in your face exciting whitewater adventure, this river provides all sorts of different types of adventures.

Rafting
Riley
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Downtown Shopping - From the Farmer's Market on Thursdays in the summer, to the headlining acts at the Avalon and the Mesa Theaters all year round, downtown Grand Junction has a cornucopia of stores, restaurants, and events for the entire family.

Downtown Grand Junction
Riley
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Ski and Hike The Grand Mesa -  Year around activities on top of the 10,000 foot 'flat top' mountain. From Powderhorn Ski resort to the Grand Mesa Lodge, you can enjoy skiing, biking, hiking, fishing, camping, snowmobiling and be one with nature.

Grand Mesa Fall colors
Zane Mathews
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There are several other unique Grand Junction experiences.

Country Jam (yes, technically it's in Mack, but Junction sort of claims it) Four days in June of Country music, friends, family food and drink.

JUCO - The Junior College World Series is held here every year at Suplizio Stadium. If you are a baseball junkie, those 7 days in May-June will fill you up.

What else is unique to Grand Junction?

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